anndata

Quick Review

Excellent skill for working with AnnData objects in single-cell genomics. The description clearly identifies when to use this skill (AnnData objects, h5ad files, single-cell RNA-seq). SKILL.md provides comprehensive coverage with quick start examples, core capabilities overview, and references to detailed documentation files. Task knowledge is outstanding with complete working examples for common workflows (single-cell analysis, batch integration, large datasets), concrete code snippets, and troubleshooting guidance. Structure is well-organized with a clear overview and proper delegation of detailed content to reference files. Novelty is strong: while a CLI agent could theoretically handle basic Python tasks, the domain-specific knowledge about AnnData internals, scverse ecosystem integration, memory-efficient practices (sparse matrices, backed mode, categoricals), and specialized workflows (batch integration, quality control pipelines) would require extensive trial-and-error and many tokens. This skill meaningfully reduces complexity for biological data analysis tasks.